Anti-PLA2G12A Antibody

PLA2G12A (Phospholipase A2 Group XIIA) is a calcium-independent phospholipase that catalyzes the hydrolysis of the sn-2 acyl bond of phospholipids, releasing free fatty acids and lysophospholipids. This primary antibody from Antibodies.com is a rabbit polyclonal reagent raised against human PLA2G12A, supplied as 100 µl of unconjugated IgG in a format suitable for western blot analysis of cell and tissue lysates.

The antibody specifically recognizes human PLA2G12A and has been validated for western blot detection of endogenous protein levels. Researchers studying lipid metabolism, phospholipid signaling, and inflammatory cascades can use this reagent to probe PLA2G12A expression across various human cell lines and primary tissues. The unconjugated format allows flexibility in downstream labeling: secondary antibody conjugates, fluorescent tags, or enzymatic reporters can be selected to match specific detection platforms.

As a polyclonal reagent, this antibody targets multiple epitopes on PLA2G12A, which can improve detection sensitivity across different protein isoforms or post-translational modifications compared to monoclonal alternatives. The rabbit host and IgG isotype are compatible with most standard anti-rabbit secondary detection systems.

Storage recommendations include aliquoting to avoid repeated freeze-thaw cycles and storing at -20°C for long-term stability. For short-term use, refrigerated storage is acceptable for several weeks. Each lot is quality-controlled to confirm specificity in western blot applications against human samples.