Anti-PLA1A Antibody

Polyclonal primary antibodies targeting phospholipase enzymes support lipid metabolism research where precise isoform detection is needed. This rabbit-derived reagent from Antibodies.com specifically recognizes PLA1A, also designated as phosphatidylserine-specific phospholipase A1, a hydrolase that cleaves fatty acids at the sn-1 position of glycerophospholipids and contributes to membrane lipid remodeling and inflammatory signaling cascades.

Prepared as an IgG isotype in unconjugated format, the antibody offers flexibility for selection of secondary detection reagents and labeling chemistries. It is validated for Western Blot applications and reacts with both human and mouse samples, enabling cross-species work in cell line panels, primary tissue lysates, and relevant animal models. The 100 µL vial volume supports multiple experimental runs when aliquoted appropriately.

PLA1A expression has been investigated in contexts including hepatocellular carcinoma and hepatic lipid processing, where the enzyme's role in generating lysophospholipid mediators has biological relevance. For storage, short-term refrigeration at 4 °C with prepared aliquots is recommended; long-term preservation is achieved by freezing at -20 °C or lower, with protection from light to safeguard reagent integrity. Avoid repeated freeze-thaw cycles by preparing single-use aliquots before storage.