Anti-PKLR Antibody

This rabbit polyclonal IgG reagent from Antibodies.com targets pyruvate kinase, liver and red blood cell (PKLR), a glycolytic regulatory enzyme encoded by a single gene that produces both the erythroid (R-type) and hepatic (L-type) isoforms via tissue-specific promoters. Researchers investigating hereditary nonspherocytic hemolytic anemia, red cell ATP maintenance, or hepatic gluconeogenesis apply this unconjugated primary antibody in Western blot (WB) and immunohistochemistry (IHC) workflows on human tissue samples. The 50 µl aliquot is supplied as a liquid fraction, validated for human reactivity, and supports immunoblotting of PKLR isoform expression alongside chromogenic IHC localization in liver and erythroid lineage cells. Aliquot storage at freezer temperatures helps preserve antibody activity across repeated freeze-thaw cycles for ongoing PKLR studies in metabolic and hematologic research.