Anti-PKC δ (phospho-S645) Antibody

Phosphorylation at serine 645 in the activation loop of protein kinase C delta marks the catalytically active form of this serine/threonine kinase, which participates in apoptosis, oxidative stress, and proliferative signaling cascades. This Antibodies.com rabbit polyclonal reagent allows researchers to monitor PKC delta activation status specifically at the phospho-S645 epitope, with validated reactivity against human, mouse, and rat samples.

The unconjugated antibody is supplied at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide at approximately pH 7.2, and is recommended for western blot analysis of cell and tissue lysates as well as immunohistochemistry on fixed tissue sections. The 100 µl volume and polyclonal clonality offer flexibility in downstream assay design, since the reagent can be paired with different secondary reporters and dilution protocols according to the experimental workflow.