Anti-PIWIL4 Antibody

PIWIL4 (Piwi-like RNA-mediated gene silencing 4), also referred to as HIWI2, belongs to the Argonaute family of proteins and partners with piwi-interacting RNAs to guide silencing of transposable elements in the germline. This rabbit polyclonal reagent from Antibodies.com targets human PIWIL4 and is supplied as 100µl of unconjugated antiserum, ready for dilution into standard immunodetection workflows.

Validated for Western blot, immunohistochemistry, and immunofluorescence, the antibody recognizes mouse and rat PIWIL4 in addition to the human protein, enabling comparative work across common model systems. Researchers commonly apply it to investigate piRNA pathway activity during spermatogenesis, examine aberrant PIWIL4 expression in tumor tissue, or map subcellular localization in germ cell and somatic contexts. For best results, store aliquots refrigerated at 4 °C, avoid repeated freeze-thaw cycles, and protect from light when paired with fluorescent secondary detection.

Each lot is affinity-purified and quality-controlled to confirm specificity for the PIWIL4 target, supporting reproducible signal in both denaturing lysates and fixed-sample preparations.