Anti-PIP5KIγ Antibody

Supplied as a 100 µl liquid aliquot at 1 mg/ml, this polyclonal antibody from Antibodies.com is raised in rabbit and provided unconjugated for direct Western blot detection of the phosphatidylinositol-4-phosphate 5-kinase gamma isoform (PIP5KIγ, gene symbol PIP5K1C). The reagent is formulated in PBS containing 0.1% sodium azide and 50% glycerol as a cryoprotectant, and its reactivity has been verified against human, mouse, and rat samples.

PIP5KIγ catalyzes the phosphorylation of phosphatidylinositol 4-phosphate to produce phosphatidylinositol 4,5-bisphosphate, a membrane phosphoinositide involved in actin cytoskeleton organization, focal adhesion dynamics, clathrin-mediated endocytosis, and synaptic vesicle recycling. The antibody is suited to immunoblotting of cell and tissue lysates, supporting research into neuronal signaling, chemotaxis, and membrane trafficking. To preserve activity, aliquot the vial upon arrival and store at -20°C, returning each portion to the freezer immediately after use to avoid repeated freeze-thaw cycles of the stock.