Anti-PIP5K1B Antibody

PIP5K1B (phosphatidylinositol-4-phosphate 5-kinase type 1 beta) is a lipid kinase that catalyzes phosphorylation of phosphatidylinositol 4-phosphate to generate phosphatidylinositol 4,5-bisphosphate (PIP2), a key phosphoinositide at the inner leaflet of the plasma membrane. This Antibodies.com rabbit polyclonal reagent is raised against the human target and validated for Western blot and immunohistochemistry workflows, with the unconjugated IgG formulation supplied as 100 µl of antiserum suitable for both applications on human samples.

The antibody supports studies of synaptic vesicle cycling, focal adhesion turnover, and membrane trafficking, where PIP5K1B-driven PIP2 production interfaces with actin remodeling and small GTPase signaling. Researchers using this reagent commonly probe lysates from cultured human cell lines to follow endogenous kinase expression, or apply it to fixed tissue sections to localize PIP5K1B in neuron-enriched regions such as the hippocampus and cerebellum. It is intended for research use only.