Anti-PIP4K2A Antibody

Phosphatidylinositol-5-phosphate 4-kinase type II alpha (PIP4K2A) is a lipid kinase that phosphorylates phosphatidylinositol 5-phosphate at the D4 position of the inositol ring, generating phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). It plays an essential role in phosphoinositide signaling, regulating membrane trafficking, cytoskeletal dynamics, insulin signaling, and cellular stress responses. PIP4K2A has been investigated in several malignancies and metabolic disorders as a node of interest in lipid second-messenger pathways.

This rabbit polyclonal reagent from Antibodies.com is validated for Western blot (WB) and immunohistochemistry (IHC) workflows and shows reactivity against human, mouse, and rat samples. It is supplied unconjugated at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% Glycerol, allowing users to pair it with their preferred secondary detection reagents. The 100 µl vial format supports multiple experimental setups, including titration optimization for tissue sections and lysate-based detection. Store refrigerated at 2 to 8 degrees C, and avoid repeated freeze-thaw cycles to preserve antibody activity for downstream cell culture and signaling studies.