Anti-PIN1 Antibody

PIN1 (Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) is a highly conserved phosphorylation-directed isomerase that regulates substrates involved in cell cycle progression, transcription, and stress response signaling. Aberrant expression of this isomerase has been linked to oncogenesis, where it drives pro-proliferative pathways, and to tau-related neuropathology in Alzheimer's disease, making it a compelling target in both cancer biology and neurodegeneration research.

This polyclonal antibody from Antibodies.com is raised in rabbit and supplied as an unconjugated, affinity-purified reagent at 1 mg/ml in PBS with 0.1% Sodium Azide and 50% Glycerol for improved shelf stability. The vial contains 100 µl of working solution, supporting routine immunodetection across western blot, immunohistochemistry, and immunofluorescence workflows. Demonstrated reactivity against human, mouse, and rat samples enables cross-species experimental design in cell-based and tissue-based studies, while the polyclonal format allows recognition of multiple epitopes on the PIN1 target.

For best results, aliquot upon arrival to limit freeze-thaw cycles and store at -20°C, protected from light. The glycerol-containing buffer preserves antigen-binding activity across repeat uses. For research use only.