Anti-PIM2 Antibody

This rabbit polyclonal reagent from Antibodies.com targets human PIM2, a constitutively active serine/threonine kinase of the PIM family that shares close homology with PIM1 and PIM3. Supplied as 100 µl of unconjugated antiserum, the antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows. PIM2 lacks a regulatory domain, so its expression is controlled mainly at the transcriptional and translational level, making antibody-based detection of endogenous protein especially useful for studies of B-cell biology, multiple myeloma, and other hematological malignancies where this kinase is frequently overexpressed. Researchers can use this reagent to track PIM2 across cell lysate preparations and formalin-fixed tissue sections, supporting investigations into mTOR pathway crosstalk, 4E-BP1 regulation, and BAD phosphorylation events relevant to oncogenic signaling networks.