Anti-PIM1 Antibody

Antibodies.com supplies this recombinant rabbit monoclonal antibody raised against PIM1, a serine/threonine kinase encoded by a proto-oncogene involved in cell cycle progression, survival signaling, and apoptosis regulation. The unconjugated reagent is supplied in a single vial at 100 µl in TBS buffer (pH 7.4) containing 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative, supporting refrigerated storage between uses for routine bench handling.

PIM1 is studied extensively in cancer research, particularly in hematological malignancies and prostate cancer, where its overexpression contributes to tumor cell proliferation and therapy resistance. The antibody enables detection by western blot, immunocytochemistry, immunofluorescence, and immunohistochemistry on fixed cells and tissue sections, allowing visualization of endogenous PIM1 expression in human and mouse specimens as well as in vitro cultured cell models.

Because the reagent is a recombinant rabbit monoclonal, lot-to-lot consistency is high and background is minimized in demanding immunocytochemistry and immunofluorescence workflows. Researchers investigating signal transduction downstream of cytokine receptors, JAK/STAT pathways, and B-cell development routinely use PIM1 antibodies to assess kinase abundance and activation state across experimental treatments and disease models.