Anti-PIK3R3 Antibody

Raised in rabbit against phosphoinositide 3-kinase regulatory subunit 3 (PIK3R3, also called p55γ), this unconjugated polyclonal IgG from Antibodies.com serves as a versatile detection reagent for the adapter subunit of class IA PI3K, the protein that pairs with the p110 catalytic subunit to drive PI3K/AKT signaling downstream of activated receptor tyrosine kinases. Supplied as a 200 µl antiserum, the reagent is validated for Western blot, immunohistochemistry, and immunofluorescence workflows and is reactive specifically with human PIK3R3, supporting studies of insulin-like growth factor signaling, cell proliferation, migration, and survival pathways in cancer cell models where PIK3R3 overexpression has been reported to correlate with tumor progression and chemoresistance. As a polyclonal reagent, it offers multi-epitope recognition useful for detecting both full-length PIK3R3 and putative isoform variants, and its unconjugated format allows researchers to pair it with HRP, biotin, or fluorophore-conjugated secondary antibodies matched to their preferred detection chemistry. The IgG isotype is compatible with standard Protein A/G purification and standard blocking protocols. Store refrigerated at 4°C in single-use aliquots to preserve antibody titer for long-term projects; protect from light and avoid repeated freeze-thaw cycles. For research use only; not intended for diagnostic or therapeutic applications.