Anti-PIK3CA Antibody

This rabbit polyclonal IgG antibody targets the p110α catalytic subunit encoded by the PIK3CA gene, a key mediator in the PI3K/AKT signaling cascade and one of the most frequently mutated oncogenes across human cancers, including breast, colorectal, and endometrial tumors. Supplied as an unconjugated reagent in a 100 µl volume, it is validated for western blot, immunohistochemistry, immunoprecipitation, and flow cytometry workflows, supporting research into driver mutations such as E545K and H1047R. The antibody shows reactivity against human, mouse, and rat samples, making it useful for cross-species studies of PI3K pathway dysregulation. For best results, store refrigerated and protect from light; avoid repeated freeze-thaw cycles by aliquoting upon receipt. Provided by Antibodies.com, this polyclonal reagent offers a flexible tool for labs investigating oncogenic signaling, pathway activation, and targeted therapy response.