Anti-PIK3C3 Antibody

Generated against human PIK3C3 (also called VPS34), this rabbit polyclonal IgG antibody detects the catalytic subunit of class III phosphatidylinositol 3-kinase, the lipid kinase that produces phosphatidylinositol 3-phosphate to drive autophagosome biogenesis and endosomal membrane trafficking. Researchers working on autophagy, amino acid signaling, receptor downregulation, and vesicular sorting use the reagent to monitor endogenous protein expression and tissue distribution across human and mouse systems. Provided as 50 µl of unconjugated antiserum, it is validated for western blot and immunohistochemistry workflows, supporting reproducible detection of full-length PIK3C3 as well as cleavage products and phosphorylation-dependent mobility shifts. The polyclonal format broadens epitope coverage, an advantage when probing mutant constructs or comparing closely related isoforms. Aliquot on arrival, avoid repeated freeze-thaw cycles, and keep the vial refrigerated to preserve long-term activity. Affinity purification at Antibodies.com delivers lot-to-lot consistency suitable for quantitative densitometry, dose-response immunoblotting, and imaging studies.