Anti-PIK3C3 Antibody

This rabbit polyclonal IgG antibody from Antibodies.com targets PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3), the catalytic subunit of class III PI3K also known as VPS34. PIK3C3 is essential for autophagy initiation and endosomal trafficking, where it phosphorylates phosphatidylinositol to generate PI3P at nascent autophagosomes and endosomal membranes. The unconjugated antibody is supplied as 100 µl of polyclonal IgG raised in rabbit, validated for western blot and immunohistochemistry applications on human and mouse samples. Researchers investigating autophagy flux, endosome maturation, mTOR signaling, and vesicle transport use anti-PIK3C3 antibodies to monitor autophagosome biogenesis and the recruitment of downstream effectors such as Beclin-1 and ATG14L. For long-term use, aliquot the antibody and store at -20 °C, avoiding repeated freeze-thaw cycles. Intended for research use only.