Anti-PIGW Antibody

Phosphatidylinositol glycan anchor biosynthesis class W (PIGW) is the target of this rabbit polyclonal antibody from Antibodies.com, supplied as 100 µl of unconjugated reagent at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol. PIGW is an endoplasmic reticulum-resident acyltransferase that adds a palmitoyl chain to the inositol ring of glycosylphosphatidylinositol (GPI) anchors, a step required for the maturation and plasma-membrane trafficking of GPI-anchored proteins. Validated for Western blot on human, mouse, and rat samples, the polyclonal format broadens epitope coverage and is well-suited to detecting endogenous PIGW in transfected cell lines, knockout controls, and primary tissue lysates. The 50% glycerol cryoprotectant permits storage at -20°C with limited freeze-thaw cycles, while 0.1% sodium azide keeps the preparation stable when refrigerated for routine bench use. Researchers investigating GPI-anchor biosynthesis, mammalian cell-surface protein tethering, and ER membrane biology will find this Antibodies.com reagent a focused tool for PIGW expression studies by Western blot.