Anti-PICK1 Antibody

PICK1 (Protein Interacting with C Kinase 1) is a PDZ-domain scaffolding protein best known for trafficking AMPA receptors at glutamatergic synapses, regulating ASIC channels, and modulating dopamine transporter surface expression. This rabbit polyclonal antibody from Antibodies.com is raised against the endogenous target and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples. Supplied as 100 µl of unconjugated reagent in a single-use vial format, the reagent detects native PICK1 in fixed tissue sections and whole-cell lysates, supporting co-localization studies with associated PDZ ligands, PKCα pathway components, and receptor cargo. The polyclonal format increases the likelihood of recognizing multiple epitopes on the scaffold protein, which is useful when working with post-translationally modified PICK1 species or with limited material from primary neuronal cultures.