Anti-PIAS4 Antibody

The PIAS4 target is a SUMO E3 ligase that catalyzes post-translational modification of substrates through SUMO conjugation, modulating transcription factor activity, chromatin organization, and the DNA damage response. This unconjugated rabbit polyclonal reagent from Antibodies.com recognizes PIAS4 in both human and mouse sample contexts, making it useful across comparative and translational studies. It is validated for Western Blot detection of denatured protein lysates and for Immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections, where it supports localization studies of nuclear SUMO pathway components. Supplied as 100 µl of unconjugated antisera, the antibody enables flexible downstream labeling with HRP, fluorophore, or biotin conjugates chosen by the end user, and it performs well across standard immunoblotting and chromogenic IHC workflows.