Anti-PIAS4 Antibody [10-24.6]

The Mouse monoclonal clone 10-24.6 from Antibodies.com targets PIAS4 (Protein Inhibitor of Activated STAT 4), a SUMO E3 ligase that catalyzes conjugation of SUMO onto substrate proteins involved in transcriptional regulation, the DNA damage response, and innate immune signaling. Supplied unconjugated in a liquid format at 100 µl per vial, the reagent is validated for western blot (WB), immunoprecipitation (IP), and immunofluorescence (IF) workflows on human samples. For storage, aliquot the antibody and store at -20 °C; avoid repeated freeze-thaw cycles to preserve binding activity. Researchers commonly use clone 10-24.6 to investigate PIAS4-mediated sumoylation of targets such as p53 and LEF1 in cancer biology and chromatin studies.