Anti-PIAS1 Antibody

Raised in rabbit against the PIAS1 protein, this unconjugated polyclonal reagent from Antibodies.com targets a SUMO E3 ligase that governs transcriptional control and chromatin remodeling in human cells. The antibody is supplied as a 100 µl volume and has been validated for western blot and immunohistochemistry workflows, supporting studies of PIAS1-mediated sumoylation, STAT1 signaling, and stress-induced DNA damage responses.

PIAS1 (Protein Inhibitor of Activated STAT 1) catalyzes the conjugation of SUMO to substrate proteins and participates in innate immunity, p53 pathway regulation, and androgen receptor-driven transcription. Confirmed reactivity against human PIAS1 makes the reagent well suited to fixed paraffin-embedded tissue sections in immunohistochemistry and to standard immunoblotting of whole-cell lysates. For best results, store refrigerated, aliquot on arrival, and protect from light; repeated freeze-thaw cycles of the antibody solution should be avoided.