Anti-PI3K p85α Antibody

Raised in rabbit and affinity-purified to recognize the p85α regulatory subunit of class IA phosphoinositide 3-kinase, this unconjugated polyclonal antibody from Antibodies.com is supplied as 100 µl of a 1 mg/ml stock in PBS containing 0.1% sodium azide and 50% glycerol. The reagent is validated for western blot (WB) and immunohistochemistry (IHC) workflows and cross-reacts with human, mouse, and rat samples, supporting studies of the PI3K/AKT signaling cascade in cancer biology, insulin response, and growth-factor-driven pathways. PIK3R1-encoded p85α stabilizes the p110 catalytic isoform at the membrane and modulates its lipid-kinase activity, making it a frequent marker in research on proliferation, survival, and metabolic signaling. The antibody is provided as a liquid aliquot that should be stored refrigerated; aliquoting upon receipt minimizes repeated freeze-thaw cycles and preserves binding activity for downstream assays.