Anti-PI3 Kinase p110 beta Antibody

This rabbit polyclonal antibody from Antibodies.com targets the catalytic subunit p110 beta of class I phosphoinositide 3-kinase (PI3K), a lipid kinase central to PI3K/AKT signaling and downstream control of cell growth, proliferation, glucose metabolism, and survival.

PIK3CB (p110 beta) is functionally distinct from the better-characterized p110 alpha subunit and has been linked to roles in insulin signaling, platelet biology, and tumor progression, particularly in PTEN-deficient cancer contexts. The reagent is supplied as 100 µl of unconjugated antisera raised in Rabbit and is validated for Western blot (WB) and immunofluorescence (IF) workflows on Human samples.

As a polyclonal reagent, the antibody recognizes multiple epitopes on p110 beta, supporting signal detection across applications where the target is expressed at low to moderate levels. The unconjugated format allows researchers to pair it with their own secondary antibody and detection chemistry, including HRP, fluorophore, or biotin conjugates.

Typical experimental uses include western blot analysis of PIK3CB expression across cell lines and primary tissues, IF localization studies in cultured cells or fixed tissue sections, and confirmation of p110 beta involvement in signaling-focused research projects. The product is shipped as a 100 µl liquid aliquot and should be stored refrigerated to preserve antibody activity over its working shelf life.