Anti-PI-9 Antibody

The PI-9 target, also known as SERPINB9, belongs to the intracellular serpin family and acts as a physiological inhibitor of granzyme B, helping to shield host cells from granzyme B-induced apoptosis. This unconjugated rabbit polyclonal reagent from Antibodies.com is supplied as a 100 µl liquid aliquot and has been validated across western blot, immunohistochemistry, and ELISA workflows in human, mouse, and rat samples. Its polyclonal format broadens epitope recognition, which is useful when mapping SERPINB9 expression in cytotoxic T lymphocytes, dendritic cells, and immune-privileged sites such as the placenta and testis where PI-9 is constitutively elevated. Leaving the antibody unconjugated gives the end user freedom to pair it with HRP, biotin, or fluorophore-labelled secondary reagents of their choice. Cross-reactivity across mouse, rat, and human specimens also supports parallel work in rodent disease models and patient-derived material for studies of immune regulation, cytotoxic granule biology, and tumor immune evasion.