Anti-PI 3-kinase p110α Antibody

Raised in rabbit as a polyclonal reagent, this unconjugated primary antibody targets the catalytic p110α subunit of phosphoinositide 3-kinase (PI3K), a lipid kinase central to the PI3K/AKT signaling cascade that governs cell growth, survival, and metabolism. The antibody recognizes the human and mouse p110α protein and is validated for Western blot, immunohistochemistry, and ELISA workflows, supporting studies of receptor tyrosine kinase signaling, insulin pathway biology, and the oncogenic PIK3CA mutations frequently encountered in breast, colorectal, and endometrial cancer research.

Supplied as 100 µl in a single-use vial, the reagent supports immunoblotting of phosphorylated downstream effectors, tissue section staining for tumor marker profiling, and plate-based detection assays. Researchers investigating class IA PI3K isoform expression, AKT pathway activation, or therapeutic target validation rely on polyclonal p110α reagents from Antibodies.com for broad epitope coverage that helps maintain signal across truncated or mutant protein variants in cell lysate and fixed-tissue preparations.