Anti-PHKA2 Antibody

Rabbit polyclonal reagent for PHKA2, the X-linked gene encoding the alpha-2 regulatory subunit of phosphorylase kinase. Mutations in this locus cause glycogen storage disease type IXa (GSD IXa), placing the protein at the center of hepatic glycogen metabolism research. The unconjugated primary antibody is validated by Antibodies.com for western blot and immunohistochemistry on human samples, supplied in a 100 µl volume suited to multiple blotting and staining experiments.

Investigators studying phosphorylase kinase complex assembly, glycogen phosphorylase regulation, and the molecular pathology of pediatric glycogenoses use this reagent to probe expression of the regulatory alpha subunit in patient-derived material. Aliquot upon receipt and limit freeze-thaw cycles to preserve antibody activity during long-term storage at standard refrigerator conditions. The polyclonal host species (Rabbit) enables recognition of multiple epitopes, supporting reliable detection of endogenous PHKA2 protein in cell lysates and fixed tissue sections relevant to GSD IXa studies.