Anti-PHKA1 Antibody

PHKA1 encodes the alpha regulatory subunit of phosphorylase kinase, an enzyme complex central to glycogen mobilization in skeletal muscle and a gene implicated in X-linked glycogen storage disease type IX. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against PHKA1 and validated for Western blot and immunohistochemistry workflows on human samples, supplied as 100 µl of antibody reagent. Researchers investigating glycogen metabolism, muscle phosphorylase kinase regulation, and inherited metabolic myopathies use anti-PHKA1 antibodies to probe expression in striated muscle and to characterize variants that impair enzyme activity.

The polyclonal format provides broader epitope coverage than a monoclonal alternative, supporting detection across multiple regions of the target protein in denatured lysates and in fixed tissue sections. Host species is rabbit, allowing standard anti-rabbit HRP- or fluorescence-conjugated secondary reagents for chromogenic, chemiluminescent, or immunofluorescence readouts. Reactivity is reported for human targets, and the unconjugated preparation gives laboratories flexibility to choose their own label or to use the antibody in capture or detection set-ups. Storage and handling recommendations from the supplier should be followed to preserve titre across freeze-thaw cycles.