Anti-PGR (phospho S190) Antibody

Phospho-specific rabbit polyclonal antibody raised against human progesterone receptor (PGR) phosphorylated at serine 190, supplied as 100 µl of unconjugated IgG by Antibodies.com. The reagent is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples, supporting studies of ligand-dependent and ligand-independent activation of this nuclear receptor in breast cancer cell models, reproductive tissue, and hormone signaling research. Working aliquots should be stored at -20 °C to limit freeze-thaw cycles, and the vial should be protected from light during handling. The polyclonal format provides broad epitope coverage around the phospho-S190 site within the N-terminal transactivation domain, a region where phosphorylation modulates cofactor recruitment and downstream transcriptional output of target genes such as those involved in cell cycle and differentiation programs.