Anti-PGR Antibody

Raised in rabbit against the human progesterone receptor (PGR), this unconjugated polyclonal reagent from Antibodies.com targets a ligand-activated nuclear transcription factor central to progesterone signaling in reproductive and hormone-responsive tissues. The antibody recognizes an epitope of the human PGR protein (UniProt P06401) and cross-reacts with the rodent ortholog in mouse and rat samples, supporting comparative studies in reproductive biology, implantation, and hormone-dependent tumor models.

Validated for Western blot analysis of cell and tissue lysates and for immunohistochemistry on formalin-fixed, paraffin-embedded sections, the reagent reveals the characteristic nuclear staining pattern observed in epithelial cells of breast and endometrial tissue. The IgG isotype offers flexibility to pair with HRP- or fluorophore-conjugated secondary reagents for either chromogenic or fluorescence detection workflows.

The antibody is supplied as a 50 µL liquid aliquot in a vial. Store frozen at -20 °C in working aliquots to limit freeze-thaw cycles, protect from light, and bring briefly to room temperature before use. For research use only; not intended for diagnostic procedures.