Anti-PGF Antibody

Placental Growth Factor (PGF) is a member of the vascular endothelial growth factor (VEGF) family and acts as a key regulator of angiogenic signaling in both physiological and pathological contexts. This unconjugated rabbit polyclonal reagent from Antibodies.com specifically targets PGF and is validated for Western blot (WB) and immunohistochemistry (IHC) workflows across human, mouse, and rat sample types, enabling comparative studies in developmental biology, tumor vascularization research, and ischemia-related disease models.

The reagent is supplied as a 100 µl aliquot at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, supporting long-term frozen storage and minimizing freeze-thaw damage for repeated experimental use. In Western blot, the antibody enables detection of endogenous PGF isoforms from tissue lysates and conditioned media, while in IHC it supports visualization of PGF expression patterns in formalin-fixed paraffin-embedded sections, particularly useful when examining placental tissue architecture and tumor microenvironment vasculature.

As a research-use antibody targeting a VEGF-pathway ligand involved in vasculogenesis, trophoblast development, and inflammatory angiogenesis, this PGF reagent serves investigators studying pre-eclampsia, cardiovascular remodeling, cancer progression, and wound healing mechanisms. The polyclonal format offers recognition of multiple epitopes on the PGF protein, which can be advantageous when working with samples that express variant isoforms or when higher signal tolerance is needed in challenging tissues.