Anti-PGC Antibody

Pepsinogen C (PGC), also known as progastricsin or pepsinogen II, is the secreted zymogen precursor of pepsin C produced by gastric chief cells, and is widely used as a marker of gastric mucosal differentiation, gastric atrophy, and gastric cancer biology in both basic and translational research. This rabbit polyclonal anti-PGC antibody from Antibodies.com is supplied as an unconjugated reagent in a 100 µl vial and is validated for western blot (WB) and immunohistochemistry (IHC) workflows across human, mouse, and rat samples. Researchers studying digestive enzyme regulation, gastric physiology, or pepsinogen II expression in tissue rely on the polyclonal reagent's broad species reactivity and unconjugated format, which can be paired with HRP, fluorescent, or biotin secondary detection systems chosen by the end user. The antibody is intended for research use only and is suited to probing PGC abundance in cell lysates and formalin-fixed tissue sections where chief cell marker expression is being characterized.