Anti-PGA5 Antibody

Raised in rabbit against the human pepsinogen A5 (PGA5) zymogen, this unconjugated polyclonal IgG reagent from Antibodies.com is configured for immunoblotting workflows on human-derived samples. The 200 µl aliquot is supplied as a liquid preparation suitable for Western blot detection of pepsinogen A, the inactive precursor of pepsin A that gastric chief cells secrete into the stomach lumen before acid-mediated activation.

PGA5 belongs to the aspartic protease family and sits alongside other closely related pepsinogen genes expressed in the gastric mucosa. Research groups studying gastric physiology, Helicobacter pylori-associated mucosal remodeling, or serum-based screening for atrophic gastritis and gastric cancer use anti-pepsinogen antibodies to track chief-cell differentiation and zymogen processing in tissue lysates and epithelial cell extracts.

Aliquot the antibody upon receipt and refrigerate for routine short-term use; for extended storage, keep frozen at -20 °C in working volumes and limit freeze-thaw cycles to preserve titer. The reagent is provided in a vial format, unconjugated, with rabbit IgG as the isotype and reactivity validated for human samples by Western blot.