Anti-PGA4 Antibody

This rabbit polyclonal antibody from Antibodies.com targets human pepsinogen A4 (PGA4), a gastric zymogen secreted by chief cells of the gastric mucosa that is converted into the digestive aspartic protease pepsin A under acidic conditions in the stomach. The unconjugated reagent is supplied as 100 µl of polyclonal antiserum raised in rabbit and is validated for Western blot and immunohistochemistry workflows on human-derived samples. Because pepsinogen expression is largely restricted to gastric epithelium and a few extra-gastric tissues, this reagent is useful for studies of gastric mucosal biology, digestive enzyme regulation, and tissue-specific protein expression patterns in archival formalin-fixed specimens as well as in lysate-based immunoblotting. The polyclonal format provides recognition of multiple epitopes across the pepsinogen A4 precursor, supporting robust detection in both denaturing gel and section-based assays. Shipped as a single-use aliquot for research use only, this Antibodies.com primary antibody gives investigators a reliable tool for probing human pepsinogen biology.