Anti-PFKFB3 Antibody

Produced by Antibodies.com as a research-grade rabbit polyclonal reagent, this unconjugated IgG antibody targets PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3), the bifunctional glycolytic regulator that controls intracellular levels of fructose-2,6-bisphosphate and drives the Warburg-style metabolic shift observed in many proliferating and tumor-associated cells.

The antibody is supplied at 200 µl per vial and is validated for Western blot and immunohistochemistry on human samples, making it relevant for studies of cancer cell metabolism, endothelial angiogenic signaling, and inflammatory activation pathways where PFKFB3 expression is mapped in tissue context. As a polyclonal reagent raised in rabbit, it offers broader epitope coverage than a monoclonal clone, which is useful when probing endogenous PFKFB3 that may show splice-variant or post-translational heterogeneity across tumor and stromal compartments.

Researchers working on glycolysis, the tumor microenvironment, or vascular remodeling will find it compatible with standard chromogenic IHC protocols and standard chemiluminescent WB workflows, and the unconjugated format allows downstream pairing with HRP or fluorophore-labeled secondary antibodies of the researcher's choice.