Anti-PFKFB3 Antibody

This rabbit polyclonal IgG antibody targets PFKFB3, the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform that fuels glycolytic flux in actively proliferating cells through synthesis of the allosteric activator fructose-2,6-bisphosphate. Investigators working on tumor metabolism, angiogenesis, and ischemic injury study this enzyme because of its elevated expression in transformed cell lines and its contribution to the Warburg effect.

Supplied by Antibodies.com as 100 µL of unconjugated polyclonal serum raised in a rabbit host, the reagent is validated for Western blot and immunohistochemistry on human tissue sections and lysates. The IgG isotype pairs cleanly with commonly available anti-rabbit secondary reagents in chromogenic, chemiluminescent, and fluorescence workflows. Storage at -20 °C in working aliquots protects activity across repeated freeze-thaw cycles, and the unconjugated format gives researchers full flexibility over labeling, blocking, and detection chemistry.