Anti-PEX5 Antibody

PEX5 is the cytosolic receptor that ferries peroxisomal matrix proteins carrying a type 1 peroxisomal targeting signal into the organelle, where it docks at the translocation machinery and is recycled for further cargo rounds. This unconjugated rabbit polyclonal reagent from Antibodies.com recognises that import factor across human, mouse, and rat samples, supporting Western blot and immunohistochemistry workflows in labs studying peroxisome biogenesis, PTS1-mediated cargo translocation, and disorders of peroxisomal assembly including Zellweger spectrum conditions.

Each vial contains 100 µl of antisera, supplied unconjugated so HRP, alkaline phosphatase, biotin, or fluorophore-labelled secondary reagents can be chosen to match a lab's existing detection chemistry. Polyclonal coverage broadens the range of PEX5 epitopes bound per blot or tissue section, which is useful when tracking low-abundance peroxisomal pools, following import-defective isoforms, or comparing expression across developmental stages and disease models. Translational projects on peroxisomal contributions to fatty acid oxidation, redox balance, and organelle inheritance in cancer and metabolic disease benefit from cross-reactivity to all three listed species.

For storage and handling, aliquot the vial upon arrival, refrigerate, and protect from light to preserve antibody activity through freeze-thaw cycles. Antibodies.com includes reactivity and application documentation with each preparation.