Anti-PEX5 Antibody

Polyclonal rabbit antibody raised against peroxisomal biogenesis factor 5 (PEX5), the cytosolic PTS1 receptor that shuttles newly synthesized matrix proteins bearing a C-terminal SKL-type peroxisomal targeting signal from the cytosol into the peroxisomal lumen. Supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a 100 µl aliquot, the unconjugated format pairs cleanly with a broad choice of secondary reagents and chromogenic or fluorescent detection chemistries. Researchers studying peroxisome biogenesis, Zellweger spectrum disorders, and metabolic disease pathways use PEX5 levels as a marker of peroxisomal protein import capacity. The glycerol-containing buffer allows storage at -20 °C with minimal freeze-thaw damage for routine lab use, and the 100 µl volume supports multiple Western blot and immunohistochemistry runs on human, mouse, and rat samples. This Antibodies.com reagent is validated for WB and IHC, with reactivity confirmed across the three species listed in the panel, and the polyclonal format gives multi-epitope recognition useful when working with truncated or post-translationally modified PEX5 isoforms, including the long and short PEX5 variants generated by alternative splicing.