Anti-PEX2 Antibody

PEX2, also referred to as peroxisomal biogenesis factor 2 or peroxin 2, is an integral peroxisomal membrane protein that operates as an E3 ubiquitin ligase within the PEX2/PEX10/PEX12 importomer complex. It drives peroxisomal matrix protein import by monoubiquitinating the shuttling receptor PEX5, and pathogenic variants in the PEX2 gene are associated with Zellweger spectrum disorders and broader peroxisome biogenesis deficiencies.

This rabbit polyclonal IgG reagent from Antibodies.com was raised against human PEX2 and is validated for western blot, immunohistochemistry, and flow cytometry applications. Provided as 100 µl of unconjugated antiserum, the antibody cross-reacts with both human and mouse samples, making it suitable for comparative studies of peroxisomal abundance, peroxisome proliferation responses, and PEX5 receptor turnover in mammalian cell and tissue models.