Anti-Peroxin-11B Antibody

PEX11B (Peroxin-11B) is a peroxisomal integral membrane protein that drives peroxisome proliferation through membrane fission. This rabbit polyclonal antibody from Antibodies.com is raised against human PEX11B and cross-reacts with the mouse and rat orthologs, supporting comparative studies of peroxisome biogenesis across standard laboratory model organisms.

The antibody is supplied as a 100 µl vial at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, a cryoprotectant that permits storage at -20°C without prior aliquoting. It is validated for western blot, immunohistochemistry on paraffin and frozen tissue sections, immunocytochemistry on cultured cells, and immunoprecipitation of native PEX11B-containing complexes.

PEX11B expression peaks in liver, kidney, and brain, where peroxisomal fatty acid β-oxidation is most active. Researchers studying peroxisome biogenesis disorders, peroxisome fission dynamics, or hepatic lipid metabolism apply this reagent to monitor changes in peroxisome number under metabolic stress, pharmacological challenge, or genetic manipulation. The unconjugated format pairs with both fluorescent- and HRP-conjugated secondary antibodies, fitting standard chromogenic and immunofluorescence pipelines.