Anti-Pepsinogen II (PGII) Antibody

Sourced through Antibodies.com, this purified monoclonal reagent is a mouse-derived IgG1 antibody that targets Pepsinogen II, also known in the literature as PGC, gastricsin or pepsinogen C. The clone was raised against purified human pepsinogen II as the immunogen, and the resulting antibody is supplied at the 1 mg pack size as an unconjugated, purified monoclonal preparation in phosphate buffered saline at pH 7.0, with purity reported as greater than 95% by SDS-PAGE. It is intended for use as an in vitro diagnostic (IVD) reagent in Lateral Flow and ELISA workflows, and the manufacturer notes that the product is for research use only and is not intended for diagnostic or therapeutic applications. Typical lead time is 10–14 business days from the supplier, and bulk or custom requests are available through the same listing. Reactivity is directed against human pepsinogen II, consistent with the human-derived immunogen used to generate the clone, and the molecule is presented in unconjugated form so it can be readily paired with a wide range of reporter-labeled secondary antibodies depending on the chosen assay format. Storage at 2–8 °C in the supplied PBS buffer is appropriate for short-term handling; for longer-term storage the antibody should be aliquoted to avoid repeated freeze-thaw cycles, though users should consult the accompanying documentation for the full stability profile. Related isotype controls listed alongside this reagent include Mouse IgG1 [PPV-06] and Mouse IgG1 [MOPC-21] clones, which are useful for setting up background and compensation controls in ELISA and lateral flow assay development. The combination of monoclonal specificity, IgG1 isotype, lack of conjugation, and compatibility with both Lateral Flow and ELISA platforms makes this an adaptable capture or detection reagent for assay developers working on gastric biomarker panels where pepsinogen II quantification is of interest.