Anti-PEPD Antibody

Produced by Antibodies.com as a primary antibody reagent, this rabbit polyclonal antiserum targets peptidase D (PEPD), the cytosolic metallopeptidase (EC 3.4.13.9) that hydrolyzes Xaa-Pro dipeptides during the final stages of collagen catabolism and proline recycling. Supplied unconjugated at 100 µl per vial and validated for Western blot and immunohistochemistry, the reagent detects endogenous PEPD protein in human, mouse, and rat samples, supporting studies of connective tissue turnover, wound healing, and the inherited disorder prolidase deficiency, which arises from loss-of-function variants in the PEPD gene. Investigators working on extracellular matrix remodeling, skin biology, or the metabolic fate of dietary hydroxyproline can pair this antibody with HRP- or fluorophore-conjugated secondaries to generate chromogenic or immunofluorescence readouts from cell lysates and fixed tissue sections alike.