Anti-PELP1 Antibody

This rabbit polyclonal reagent from Antibodies.com recognizes PELP1 (Proline, Glutamate and Leucine Rich Protein 1), a transcriptional coactivator also referenced as MNAR that scaffolds estrogen and androgen receptor signaling. Frequently studied in hormone-responsive cancer research, PELP1 contributes to breast, prostate, and ovarian tumor biology, where altered expression shapes ribosomal biogenesis, histone modification, and non-genomic kinase cascades downstream of nuclear receptor activation.

Shipped as 100 µl of unconjugated antiserum, the antibody is validated for Western blot and immunohistochemistry across human, mouse, and rat samples. Because the polyclonal response spans multiple epitopes, the reagent detects both full-length PELP1 and shorter isoforms, supporting chromatin- and cytoplasm-based readouts in fixed and fractionated material.

Researchers working on nuclear receptor crosstalk, ribosomal RNA processing, or epithelial-mesenchymal transition can pair this reagent with chromatin fractionation or immunoprecipitation protocols. Short-term refrigerated storage preserves working aliquots; aliquoting upon receipt and limiting freeze-thaw cycles protects antibody activity for longitudinal studies in cell culture and primary tissue research.