Anti-PEF1 Antibody

This rabbit polyclonal IgG antibody from Antibodies.com targets human PEF1 (Penta-EF hand domain-containing protein 1), a calcium-binding modulator implicated in endoplasmic reticulum stress signaling and mitochondrial apoptotic pathways. Supplied as an unconjugated reagent in a 100 µl vial, the antibody is validated for Western blot detection of endogenous PEF1 in human cell lysates and tissue homogenates. The polyclonal format recognizes multiple epitopes on the target, supporting robust detection of both native and denatured PEF1, including post-translationally modified forms that arise under oxidative stress or calcium dysregulation. Researchers studying ER-associated degradation, calcium homeostasis, and programmed cell death can apply this reagent to dissect PEF1 function in neurodegeneration and cancer disease models. The unconjugated format allows flexible pairing with HRP-, fluorophore-, or biotin-conjugated secondary reagents for Western blot imaging, strip-and-reprobe workflows, or downstream immunoprecipitation experiments. For short-term use, store the vial refrigerated at 2 to 8 degrees C in working aliquots to preserve activity and minimize freeze-thaw cycles.