Anti-PECAM1 Antibody

PECAM1 (Platelet Endothelial Cell Adhesion Molecule 1, also known as CD31) is a 130 kDa type I transmembrane glycoprotein of the immunoglobulin superfamily that is concentrated at endothelial cell junctions and is also expressed on platelets and selected leukocyte subsets. This unconjugated rabbit polyclonal antibody from Antibodies.com was raised against human PECAM1 and is validated for Western blotting and immunohistochemistry workflows on human samples. The reagent is supplied as a 100 µl liquid aliquot, suitable for multi-experiment use across vascular biology, angiogenesis, and inflammation research projects. Because CD31 marks continuous endothelium, it is widely applied to assess microvessel density in tumor sections, to characterize vascular networks in tissue models, and to track endothelial differentiation in stem cell studies. Researchers commonly apply it to formalin-fixed paraffin-embedded sections for IHC, where it produces a strong membranous staining pattern at inter-endothelial junctions, and to whole-cell lysates for WB, where the canonical band runs near 130 kDa with possible lower-molecular-weight glycoforms depending on tissue source. The polyclonal format provides epitope redundancy that can be useful when probing conserved regions of the target, and the unconjugated format allows flexible pairing with custom fluorophore, biotin, or enzyme conjugates chosen for a given detection platform. Aliquot upon first use and store refrigerated with the supplied preservative to preserve activity for repeated experiments.