Anti-PDX1 Antibody

Raised in rabbit against the PDX1 transcription factor, this polyclonal antibody from Antibodies.com detects the pancreatic and duodenal homeobox 1 protein across human, mouse, and rat samples. PDX1 governs early pancreatic organogenesis, drives insulin gene transcription in beta cells, and is a key marker in studies of islet cell differentiation, diabetes models, and beta-cell regeneration research. Supplied as 100 µL of unconjugated reagent at 1 mg/mL in PBS with 0.1% Sodium Azide and 50% glycerol, the antibody is validated for Western blot and immunohistochemistry workflows. The high-glycerol formulation allows convenient storage at -20 °C with minimal freeze-thaw damage, while the azide-containing buffer suits routine chromogenic and fluorescence-based IHC protocols on fixed tissue sections. Researchers commonly apply this reagent to track PDX1 expression during embryonic pancreas development, characterize insulin-positive beta-cell populations in rodent diabetes models, and confirm transgene induction in stem-cell-derived islet differentiation studies.