Anti-PDS5B Antibody

Antibodies.com offers this rabbit polyclonal antibody targeting PDS5B, a cohesin-associated factor required for sister chromatid cohesion and proper chromosome segregation during mitosis and meiosis.

Supplied as 200 µl of unconjugated IgG, the reagent is validated for Western blot analysis of the human protein and supports research into DNA double-strand break repair, replication fork stability, and the cohesin regulatory network.

PDS5B (also known as APRIN) contributes to the loading and release of cohesin complexes from chromatin and has been linked to androgen-induced proliferation control, making this antibody useful for studies of cell cycle progression, genome maintenance, and tumor suppressor pathways.

For best results, briefly centrifuge before opening, aliquot into working volumes, store at -20 °C, and avoid repeated freeze-thaw cycles to preserve long-term reactivity.