Anti-PDS5B Antibody

Produced as a rabbit polyclonal reagent validated for Western blot analysis of human PDS5B, this unconjugated IgG antibody from Antibodies.com detects the Sister Chromatid Cohesion Protein PDS5 Homolog B, a regulator of the cohesin complex that maintains pairing of replicated chromatids from S phase through mitosis. The affinity reagent ships as 100 µl of polyclonal antiserum for routine immunoblotting of chromatin-associated factors, genome stability pathways, and mitotic chromosome architecture. Researchers investigating cell cycle progression, homologous recombination, and DNA double-strand break repair use the antibody to probe cohesin loading and release at replication forks and sites of genotoxic stress.