Anti-PDPN Antibody

Podoplanin, encoded by the PDPN gene, is a transmembrane sialoglycoprotein widely used as a selective marker for lymphatic endothelial cells and for several cancer subtypes. This polyclonal reagent from Antibodies.com is raised in rabbit and supplied as an unconjugated IgG preparation in a 50 µl vial, ready for direct incorporation into western blot and immunohistochemistry workflows on human samples. Researchers studying tumor lymphangiogenesis, oral squamous cell carcinoma, or podocyte biology rely on PDPN immunostaining to distinguish lymphatic vessels from blood vasculature and to characterize fibroblast reticular cells in lymphoid tissue. The antibody's polyclonal format increases the chance of recognising multiple epitopes on the target, which can be useful when working with formalin-fixed paraffin-embedded tissue where antigen masking is common. For best stability, the vial should be refrigerated between uses and small aliquots prepared if freezing long-term, since repeated freeze-thaw cycles degrade IgG performance in many applications. Each lot is quality-controlled for use on human specimens, and the unconjugated format gives laboratories the flexibility to pair it with their own HRP- or fluorophore-labelled secondary antibodies for chromogenic or fluorescence detection.