Anti-PDP1 Antibody

This affinity-purified polyclonal reagent from Antibodies.com binds Pyruvate Dehydrogenase Phosphatase Catalytic Subunit 1 (PDP1), the mitochondrial Ser/Thr phosphatase that reactivates the pyruvate dehydrogenase complex by dephosphorylating its E1α subunit. PDP1 levels shift under hypoxia, during oncogenic signaling, and in metabolic disease models, giving researchers a probe to track phosphatase expression across cultured human cells and tissue samples.

Validated for Western blot and immunohistochemistry, the unconjugated Ig stock ships as 100 µl of liquid suitable for denaturing gel detection of endogenous PDP1 and for chromogenic or fluorescence staining of fixed specimens. Investigators working on carbohydrate metabolism, mitochondrial regulation, or cancer metabolism apply the antibody to lysates from cultured cells and to paraffin-embedded tissue sections, following standard blotting and IHC workflows.

Host species is Rabbit, and reactivity is reported against Human PDP1. Store refrigerated and protect from light; aliquot upon arrival to limit freeze-thaw cycles and preserve activity across multiple staining or blotting runs.