Anti-PDK1 Antibody

From the Antibodies.com catalogue, this affinity-purified reagent is a rabbit polyclonal IgG raised against a synthetic peptide derived from human PDK1 (pyruvate dehydrogenase kinase isoform 1) surrounding the non-phosphorylation site at serine 241, enabling recognition of endogenous PDK1 levels across multiple model systems. Supplied as an unconjugated liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide at a working concentration of 1 mg/mL, the 50 µl aliquot is validated for ELISA, Western blot (WB) and immunohistochemistry (IHC) applications, with demonstrated reactivity against human, mouse and rat samples. The host species is rabbit, the clonality is polyclonal, and the target is the full-length PDK1 protein (also known as PDH kinase 1, PDHK1 or mitochondrial [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1). For handling, the vial is shipped at 4 °C and, upon receipt, should be aliquoted and stored at -20 °C with freeze/thaw cycles avoided to preserve antibody integrity. This research-use-only reagent is intended for laboratory investigation of PDK1-mediated phosphorylation of the pyruvate dehydrogenase complex and related metabolic signalling pathways, and is dispatched from Antibodies.com's St. Louis facility with a typical lead time of 6–9 business days.