Anti-PDK1 Antibody

This unconjugated rabbit polyclonal antibody targets PDK1 (pyruvate dehydrogenase kinase 1), a mitochondrial serine/threonine kinase that phosphorylates and inactivates the pyruvate dehydrogenase complex to control entry of glucose-derived carbon into the TCA cycle. Produced by Antibodies.com, the reagent is supplied as 100 µl of liquid antiserum and is validated for western blot, immunohistochemistry, and ELISA workflows on human, mouse, and rat samples. The polyclonal format provides broad epitope coverage useful for recognizing full-length PDK1 as well as processed or post-translationally modified forms, and the unconjugated preparation allows pairing with HRP-, biotin-, or fluorophore-labeled secondary reagents of the user's choice for chromogenic western blot detection, fluorescence imaging, and chromogenic immunohistochemistry. Researchers studying metabolic reprogramming in cancer, insulin signaling in diabetes models, hypoxia-induced HIF pathway responses, and mitochondrial kinase regulation rely on PDK1 immunoreagents to compare expression across normal versus transformed tissues and to track pathway activation under metabolic or pharmacologic stress. The antibody is intended for research use only as a primary detection reagent in immunoassay protocols and is supplied ready to use in standard laboratory workflows.